Articles
A New Study: Sex Differences in Pharmacokinetics Predict Adverse Drug Reactions in Women
For decades, women were excluded from clinical drug trials based, in part, on unfounded concerns that female hormone fluctuations render women difficult to study said lead author Irving Zucker, a professor emeritus of psychology and of integrative biology at UC Berkeley. The findings, published in the journal Biology of Sex Differences, confirm the persistence of a drug dose gender gap stemming from a historic disregard of the fundamental biological differences between male and female bodies, Zucker said. more »
The Autobiography of a Garden at The Huntington, a Joy for Viewers and Gardeners
One life-affirming pleasure awaiting visitors will be found in The Huntington Art Gallery’s Works on Paper Room. There, displayed against walls of saturated blue, is a resonant, even elegiac, visual narrative. The story that it tells of life and renewal is not on paper, but on 12 uniquely bordered, luminous, ceramic plates revealing in keenly observed detail “The Autobiography of a Garden,” a month-to-month evolution of a real-life garden in Providence, Rhode Island. The exhibition, on view through July 5, 2021, is the work of American painter and printmaker Andrew Raftery and is the product of his inventive, modern-day approach to the transfer of print images onto ceramic, a process dating back to the mid-18th century. Also on view at RISD is Beth Katelman's exhibit. And don't forget the Huntington's shop! more »
Exclusive: Over 900 Health Workers Have Died of COVID-19; Memorializing Every US Health Care Worker Who Dies During the Pandemic and the Toll Is Rising
Lost on the Frontline is a partnership between the two newsrooms that aims to count, verify and memorialize every US health care worker who dies during the pandemic. The tally includes doctors, nurses and paramedics, as well as crucial support staff such as hospital custodians, administrators and nursing home workers, who put their own lives at risk during the pandemic to care for others. The early data indicates that dozens have died who were unable to access adequate PPE and at least 35 succumbed after federal work-safety officials received safety complaints about their workplaces. more »
Clinical Trials of Monoclonal Antibodies to Prevent COVID-19 Now Enrolling Healthy Adults Who Are At Risk of Infection Due to Close Contact at Work or Home to Persons with SARS-CoV-2 Infection
“The COVID-19 Prevention Network is designed to conduct large-scale trials rapidly and efficiently,” said NIAID Director Anthony S. Fauci, M.D. “This network will allow us to test the safety and efficacy of monoclonal antibodies and other preventive measures to help identify how best to reduce the level of SARS-CoV-2 infection and ultimately end the COVID-19 pandemic.” Monoclonal antibodies are laboratory-made versions of proteins naturally produced by the immune system in response to invading viruses or other pathogens. Neutralizing antibodies, whether natural or monoclonal, can bind directly to portions of viruses that they use to attach to and enter cells, preventing them from initiating the infection cycle. Monoclonal antibodies may provide short-term protection from SARS-CoV-2 and could serve as important components of the COVID-19 pandemic response until vaccines become available. more »