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"Recent emergencies have highlighted the importance of preparedness. One key component of the nation's medical response infrastructure is the SNS. The SNS inventory may be deployed to state, local, territorial, tribal, and international governments when needed. GAO placed HHS's leadership and coordination of public health emergencies on its High Risk List in January 2022 (GAO-22-105291) in part due to deficiencies in HHS's management of countermeasures. The Pandemic and All-Hazards Preparedness and Advancing Innovation Act of 2019 included a provision for GAO to review the SNS. This report examines: (1) the process used to make inventory decisions; (2) non COVID-19 obligations for countermeasures and their alignment with recommendations; and (3) obligations for countermeasures using COVID-19 relief funds, and inventory and operations changes in response to the COVID-19 pandemic." more »

"Larger, more detailed epidemiologic studies are needed to further understand the clinical importance and epidemiologic consequences of COVID-19 rebound, the authors write. The authors note that the current data support the need for isolation in symptomatic rebound persons and the need to evaluate, in a clinical trial, longer courses of Paxlovid in immunocompromised individuals where the immune response may be ineffective." more »

Dr. Fauci: 'We need to make sure that in the realm of the complexity of this outbreak, from a public health standpoint, from a policy standpoint, from a scientific standpoint, the one thing that does stand out as a really unprecedented success story is how science has added to our capability in a very, very big way to address this outbreak. And even though it’s been terrible from the standpoint of the toll of human suffering and death both in the United States and globally, it clearly would have been much, much worse had it not been for what science has brought to the table. Having said that in one breath, we still must be aware of how unusual this virus is and continues to be in its ability to evolve into new variants which defy the standard public health mechanisms of addressing an outbreak where you would expect it that once a certain number of people get infected and/or get vaccinated that you could, essentially, bring an end to the pandemic component of the outbreak." more »

"GAO’s interviews with claims processors suggest that they evaluate claims for these conditions inconsistently based on inaccurate interpretations of VA’s claims processing procedures. Specifically, during interviews at three selected offices that process Agent Orange claims, GAO heard inaccurate statements about (1)when the 1-year manifestation period requirement applies and (2) what types of evidence can be used to address this requirement or to support requesting a medical opinion that could be used to support veterans’ claims. VA’s guidance does not clearly address these issues. Without clear guidance, claims processors may incorrectly apply the 1-year manifestation period requirement when veterans have evidence suggesting a direct connection to service and, in turn, could inappropriately deny benefits to some Vietnam veterans." more »