Money and Computing

"Although Horizon says it now has 20 drugs under development, in its 15 years of existence it has yet to license a product it invented. Yet the company has managed to assemble a war chest of lucrative drugs, in the process writing a playbook for how to build a modern pharmaceutical colossus. As the White House and both parties in Congress grapple with reining in prescription drug prices, Horizon’s approach reveals just how difficult this may be. Horizon’s strategy has paid off handsomely. Krystexxa was just one of the many shiny objects that attracted Amgen, a pharmaceutical giant. Amgen announced in December that it intends to buy Horizon for $27.8 billion, in the biggest pharmaceutical industry deal announced in 2022. Horizon’s CEO, Tim Walbert, who will reportedly get around $135 million when the deal closes, has mastered a particular kind of industry expertise: taking drugs invented and tested by other people, wrapping them expertly in hard-nosed marketing and warm-hued patient relations, raising their prices, and enjoying astounding revenues." more »

Ferida Wolff Writes: "I find this activity so simple and calming that I like to do it often during the nice weather. And each season nature invites us to share in the changes, to see the variety that exists naturally. I hope that everyone has access to a calming place, a space to take a deep breath and let go of any worries... An awareness of the natural connection can beautifully enhance our lives." more »

"Gender gaps in labor market activity are pervasive, longstanding, and a regular subject of policy debates. Relative to men, women tend to work fewer hours per week, more conventional hours, and fewer years over the course of their lives. These differences in the intensity and timing of work contribute to gender disparities in promotions and pay. But despite decades of research on this topic, little attention has been paid to the timing of work throughout the year. To motivate our inquiry, Figure 1 plots the monthly labor force participation rates of prime-age US women and men using non–seasonally adjusted data, with June, July, and August shaded gray. Summer after summer, women's labor force participation drops sharply while men's participation does not." more »

1) PITCH TIMER • 15 seconds with bases empty; 20 seconds with runners on • Hitter gets 1 timeout per plate appearance; must be in batter’s box with 8 seconds left • Pitchers get two disengagements (pickoff attempts or step-offs) per batter; violations are a balk • Limits on pickoff attempts led to 26% increase in stolen base attempts in Minors • Pitch timer helped reduce game length by 25 minutes in Minors in ‘22 more »