“Genomics has the potential to change reactive medicine into preventative medicine,” said Leslie Biesecker, M.D., NIH distinguished investigator, director of NHGRI’s Center for Precision Health Research and a senior author of the article. “Studying how taking a genotype-first approach to research can help us learn how to model predictive and precision medicine in the future.”

"Speier first ran for Congress in 1979, facing a crowded field in a special election for a seat formerly held by Congressman Leo J. Ryan, for whom Speier had served as a legislative aide. The special election was called after Ryan was shot to death in Jonestown, at the compound of the People’s Temple, a cult in Guyana that had previously been based in Ryan’s District. Speier traveled with Ryan on that trip in 1978 in an attempt to rescue some of the cult’s 900 members. She was left nearly lifeless on the airport tarmac after being shot five times at point blank range with an assault rifle. Speier underwent multiple surgeries after the tragedy and while recovering she realized she had a choice to make: Did she want to be a victim or did she want to be a survivor? Speier chose to be a survivor, noting that 'looking death in the face can make you fearless.'"

“Mr. Fox, and his confederate Mr. Croft, were convicted by a jury of masterminding a plot to kidnap the Governor of Michigan and to use weapons of mass destruction against responding law enforcement,” said Assistant Attorney General Matthew G. Olsen of the Justice Department’s National Security Division. “Today’s sentence reflects the Department of Justice’s unwavering commitment to protecting our elected officials, law enforcement officers, and dedicated public servants from criminal threats and violence — and to holding the perpetrators of such acts fully accountable under the law.”

Roberta McReynolds Writes: "Not a Christmas went by without the hope of discovering a brand-new box of 64 crayons to unwrap. Opening the lid released that unforgettable whiff of waxy pigments, and revealed the first glimpse of rows of those perfect tips on display that had never yet touched paper. The body of each stick was double wrapped in paper to lessen the chance of breakage. Those little paper shrouds bore the official name of each color. It was necessary to peel back the paper as the crayons wore down with usage. As I picked at the edge of the stiff paper it would inevitably slip under my short fingernails and stab the tender quick. Tearing back the paper in uneven strips ruined the perfect appearance in my eyes. One time I removed the entire paper from every single crayon to make them all uniform, and soon discovered how difficult it was to discern the differences in the darker colors. I regretted the disaster I’d created and immediately began longing for my next new box of crayons."

Jill Norgren reviews three must read books about law and justice: In Philippa Strum’s On Account of Sex: Ruth Bader Ginsburg and the Making of Gender Equality Law we learn how Ginsburg did notorious work before she became “the notorious RBG.” Ginsburg was one of the many activist women lawyers in the U.S. who have worked on behalf of issues of justice. In Lady Justice: Women, the Law, and the Battle to Save America Dahlia Lithwick introduces readers to several more, women attorneys who, during and after the Trump years, have sought justice for immigrants, would-be voters, and anti-fascist protestors among others. Rounding out these must-reads is Justice on the Brink, journalist Linda Greenhouse’s account of the U.S. Supreme Court during its 2020-2021 term when three new conservative Trump nominees along with Justices Roberts, Thomas, and Alito took full control of SCOTUS.

The new harm reduction research network will include nine research projects and one coordinating center. Grantees will investigate harm reduction strategies for their effectiveness in preventing drug overdoses and other adverse outcomes, sustainability and level of individual and community engagement. All projects will have a community advisory board and/or people with lived experience will have paid positions to support the research. Johns Hopkins University Baltimore, New York University School of Medicine New York City, Oregon Health and Science University Portland, Research Triangle Institute NC, University of Chicago, University of Nevada-Reno, University of Pittsburgh, University of Wisconsin Madison, Weill Medical College of Cornell

Based on GAO's review of regulations and information obtained from officials with the Department of Transportation (DOT) and Federal Aviation Administration (FAA), GAO found that DOT has taken steps to implement the relevant accessibility-related provisions of the FAA Reauthorization Act of 2018. For example, DOT now requires the largest U.S. airlines to report the number of wheelchairs and scooters that were transported and damaged. DOT is addressing several other provisions in the initial rulemaking processes. DOT has also taken steps to address other longstanding accessibility issues not required under the 2018 Act, but important to passengers with disabilities. In March 2022, DOT issued a proposed rule to address accessible lavatories that would apply to aircraft deliveries, to begin in 20 years. Regarding disability-related enforcement actions, DOT has taken one since 2019.

Lawrence Livermore National Laboratory: LLNL’s experiment surpassed the #fusion threshold by delivering 2.05 megajoules of energy to the target, resulting in 3.15 MJ of fusion energy output, demonstrating for the first time the fundamental science basis for inertial fusion energy. “The pursuit of fusion ignition in the laboratory is one of the most significant scientific challenges ever tackled by humanity, and achieving it is a triumph of science, engineering, and most of all, people,” LLNL Director Dr. Kim Budil said. “Crossing this threshold is the vision that has driven 60 years of dedicated pursuit — a continual process of learning, building, expanding knowledge and capability, and then finding ways to overcome the new challenges that emerged. These are the problems that the U.S. national laboratories were created to solve.” U.S. Representative Zoe Lofgren (CA-19). “This significant advancement showcases the future possibilities for the commercialization of fusion energy. Congress and the Administration need to fully fund and properly implement the fusion research provisions in the recent CHIPS and Science Act and likely more. During World War II, we crafted the Manhattan Project for a timely result. The challenges facing the world today are even greater than at that time. We must double down and accelerate the research to explore new pathways for the clean, limitless energy that fusion promises.”